I've been using Estrofem for about 12 years. I get it at a place called InhousePharmacy.vu. I've never needed a prescription, I don't know about now. I know you're not supposed to do it this way but it has worked for me. I did alot of research prior to making that decision. I had read that a normal feminizing dose was 6-8 mgs, but I've always limited myself to 4 mgs a day...1 2mg pill in the morning and one at night. I think it took longer to see any effect but I think it's safer....I've never had any problem and it's been the best thing I ever did...It's done so much to feminize me...but it is a huge step, you have to be ready and able to cope with the changes that will happen. But as I've said...for me it was the best thing to do...and it's sent me much farther along this wonderful path to womanhood...and I do love it!
Good luck Sister!
Diane